Human placental glutathione S-transferase-mediated metabolism of methyl parathion

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Human placental glutathione S-transferase-mediated metabolism of methyl parathion.

The ability of human placental glutathione S-transferase (GSHTr) to metabolize methyl parathion (MeP) was examined. MeP was found to be a substrate for both partially purified pre-term and highly purified term placental GSHTr. The characterization of the reaction by high performance liquid chromatography revealed the presence of desmethyl parathion (DesMeP) as the sole metabolite. Term placenta...

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ژورنال

عنوان ژورنال: Biochemical Pharmacology

سال: 1986

ISSN: 0006-2952

DOI: 10.1016/0006-2952(86)90614-3